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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
KPL-1 breast CTRPv21
MKN1 stomach CTRPv21
253J-BV urinary tract CTRPv21
BFTC-909 urinary tract CTRPv21
CAL-120 breast CTRPv21
CAL-29 urinary tract CTRPv21
CAL-62 thyroid CTRPv21
HuCCT1 biliary tract CTRPv21
NMC-G1 central nervous system CTRPv21
RPMI-7951 skin CTRPv21
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA DYRK1B CTRPv2 AAC 0.14 0.0002
mRNA POP4 CTRPv2 AAC 0.14 0.0002
mRNA RSC1A1 CTRPv2 AAC 0.14 0.0002
mRNA PMM1 CTRPv2 AAC -0.14 0.0002
mRNA C6 CTRPv2 AAC 0.14 0.0002
mRNA TMEM109 CTRPv2 AAC 0.14 0.0002
mRNA NDNF CTRPv2 AAC 0.13 0.0003
mRNA ALG8 CTRPv2 AAC 0.13 0.0003
mRNA CNDP2 CTRPv2 AAC 0.14 0.0003
mRNA BLNK CTRPv2 AAC 0.14 0.0003
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