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SourcesNames Used
PharmacoGx necrostatin-1

External IDs

Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Pubchem: 2828334

Annotated Targets


Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
KPL-1 breast CTRPv21
MKN1 stomach CTRPv21
253J-BV urinary tract CTRPv21
BFTC-909 urinary tract CTRPv21
CAL-120 breast CTRPv21
CAL-29 urinary tract CTRPv21
CAL-62 thyroid CTRPv21
HuCCT1 biliary tract CTRPv21
NMC-G1 central nervous system CTRPv21
RPMI-7951 skin CTRPv21
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Top molecular features associated with response to necrostatin-1

Feature TypeStandardized
Nominal ANOVA
mRNA GPR142 CTRPv2 AAC 0.15 5e-05
mRNA NARS2 CTRPv2 AAC 0.15 6e-05
mRNA URB2 CTRPv2 AAC 0.16 7e-05
mRNA BTRC CTRPv2 AAC 0.14 9e-05
mRNA PRDM15 CTRPv2 AAC 0.15 0.0001
mRNA NCAN CTRPv2 AAC 0.14 0.0001
mRNA ZNF124 CTRPv2 AAC 0.16 0.0001
mRNA OR5AK2 CTRPv2 AAC 0.14 0.0002
mRNA TIMM21 CTRPv2 AAC 0.14 0.0002
mRNA ZNF407 CTRPv2 AAC 0.15 0.0002
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