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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
COLO-680N oesophagus CTRPv21
ECC12 stomach CTRPv21
HCC-95 lung CTRPv21
JMSU-1 urinary tract CTRPv21
RH-41 soft tissue CTRPv21
23132-87 stomach CTRPv21
8305C thyroid CTRPv21
BHY upper aerodigestive tract CTRPv21
GSU stomach CTRPv21
JIMT-1 breast CTRPv21
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA STAC2 CTRPv2 AAC 0.18 2e-06
mRNA PHACTR1 CTRPv2 AAC 0.2 4e-06
mRNA FAM129C CTRPv2 AAC 0.17 5e-06
mRNA ABC13-47656900H15.1 CTRPv2 AAC 0.16 7e-06
mRNA GHRH CTRPv2 AAC 0.16 1e-05
mRNA RGR CTRPv2 AAC 0.15 3e-05
mRNA DDI2 CTRPv2 AAC 0.16 3e-05
mRNA PHF24 CTRPv2 AAC 0.15 3e-05
mRNA SLC26A5 CTRPv2 AAC 0.15 4e-05
mRNA AHCTF1 CTRPv2 AAC 0.15 5e-05
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