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SourcesNames Used
PharmacoGx necrostatin-1

External IDs

Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Pubchem: 2828334

Annotated Targets


Cell lines tested with necrostatin-1

797 cell lines have been tested with this compound, using data from 1 dataset(s).
253J urinary tract CTRPv21
ALL-SIL haematopoietic and lymphoid tissue CTRPv21
HDQ-P1 breast CTRPv21
SNU-489 central nervous system CTRPv21
SNU-626 central nervous system CTRPv21
SNU-878 liver CTRPv21
TUHR4TKB kidney CTRPv21
ACC-MESO-1 pleura CTRPv21
BCPAP thyroid CTRPv21
CGTH-W-1 thyroid CTRPv21
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Top molecular features associated with response to necrostatin-1

Feature TypeStandardized
Nominal ANOVA
mRNA STAC2 CTRPv2 AAC 0.18 2e-06
mRNA PHACTR1 CTRPv2 AAC 0.2 4e-06
mRNA FAM129C CTRPv2 AAC 0.17 5e-06
mRNA ABC13-47656900H15.1 CTRPv2 AAC 0.16 7e-06
mRNA GHRH CTRPv2 AAC 0.16 1e-05
mRNA RGR CTRPv2 AAC 0.15 3e-05
mRNA DDI2 CTRPv2 AAC 0.16 3e-05
mRNA PHF24 CTRPv2 AAC 0.15 3e-05
mRNA SLC26A5 CTRPv2 AAC 0.15 4e-05
mRNA AHCTF1 CTRPv2 AAC 0.15 5e-05
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