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MS-275

Synonyms

SourcesNames Used
GDSC1000MS-275
gCSIms275
FIMMEntinostat
CTRPv2entinostat
PharmacoGx MS-275

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
Inchikey: INVTYAOGFAGBOE-UHFFFAOYSA-N
Pubchem: 4261

Cell lines tested with MS-275

1119 cell lines have been tested with this compound, using data from 4 dataset(s).
IGROV-1 ovary gCSI, FIMM, CTRPv24
A549 lung gCSI, CTRPv24
RPMI-8226 haematopoietic and lymphoid tissue GDSC1000, gCSI, FIMM, CTRPv24
BT-474 breast GDSC1000, gCSI, FIMM, CTRPv24
K-562 haematopoietic and lymphoid tissue GDSC1000, gCSI, FIMM, CTRPv24
ES-2 ovary GDSC1000, gCSI, FIMM, CTRPv24
NCI-H1299 lung GDSC1000, gCSI, CTRPv24
OVCAR-4 ovary GDSC1000, gCSI, FIMM, CTRPv24
MV-4-11 haematopoietic and lymphoid tissue GDSC1000, gCSI, FIMM, CTRPv24
NCI-H1869 lung GDSC1000, gCSI, CTRPv24
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Top molecular features associated with response to MS-275


Feature TypeStandardized
Nominal ANOVA
mRNA CDKAL1 CTRPv2 AAC 0.22 7e-12
mRNA LAMB2 CTRPv2 AAC -0.24 9e-11
mRNA PTRF CTRPv2 AAC -0.22 3e-09
mRNA SBK1 CTRPv2 AAC 0.2 3e-09
mRNA TEX13B CTRPv2 AAC 0.18 5e-09
mRNA EHD2 CTRPv2 AAC -0.21 6e-09
mRNA FAM9A CTRPv2 AAC 0.18 9e-09
mRNA TDG CTRPv2 AAC 0.19 1e-08
mRNA MBTD1 CTRPv2 AAC 0.22 1e-08
mRNA SOX4 CTRPv2 AAC 0.18 1e-08
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