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SourcesNames Used
PharmacoGx MLN4924

External IDs

Smiles: C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
Pubchem: 71729979

Cell lines tested with MLN4924

1158 cell lines have been tested with this compound, using data from 3 dataset(s).
MDA-MB-361 breast GDSC1000, GRAY, CTRPv25
CAMA-1 breast GDSC1000, GRAY, CTRPv25
BT-474 breast GRAY, CTRPv24
A549 lung GDSC1000, CTRPv24
Hs-578-T breast GDSC1000, GRAY, CTRPv24
HCC1428 breast GDSC1000, GRAY, CTRPv24
MDA-MB-175-VII breast GDSC1000, GRAY4
BT-20 breast GDSC1000, GRAY, CTRPv24
MDA-MB-231 breast GDSC1000, GRAY, CTRPv24
UACC-812 breast GRAY3
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Top molecular features associated with response to MLN4924

Feature TypeStandardized
Nominal ANOVA
mRNA TAF5 CTRPv2 AAC 0.27 1e-12
mRNA ORC1 CTRPv2 AAC 0.26 9e-12
mRNA PCGF6 CTRPv2 AAC 0.23 2e-11
mRNA ARHGAP19 CTRPv2 AAC 0.27 1e-10
mRNA MCM6 CTRPv2 AAC 0.25 1e-10
mRNA FAM114A1 CTRPv2 AAC -0.25 5e-10
mRNA LMNB1 CTRPv2 AAC 0.23 1e-09
mRNA ATP6V1G2-DDX39B CTRPv2 AAC 0.21 1e-09
mRNA SLFN11 CTRPv2 AAC 0.21 2e-09
mRNA PRPF38A CTRPv2 AAC 0.22 2e-09
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