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SourcesNames Used
PharmacoGx AUY922

External IDs

Smiles: CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Pubchem: 10096043

Cell lines tested with AUY922

932 cell lines have been tested with this compound, using data from 1 dataset(s).
RERF-LC-MS lung GDSC10001
MN-60 haematopoietic and lymphoid tissue GDSC10001
NAMALWA haematopoietic and lymphoid tissue GDSC10001
FADU upper aerodigestive tract GDSC10001
NCI-H720 lung GDSC10001
HAL-01 haematopoietic and lymphoid tissue GDSC10001
OS-RC-2 kidney GDSC10001
NUGC-3 stomach GDSC10001
NCI-H2444 lung GDSC10001
NCI-H2009 lung GDSC10001
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Top molecular features associated with response to AUY922

Feature TypeStandardized
Nominal ANOVA
mRNA KIF1A GDSC1000 AAC -0.22 3e-08
mRNA SETBP1 GDSC1000 AAC -0.19 3e-08
mRNA TMEM108 GDSC1000 AAC -0.22 4e-08
mRNA ELAVL4 GDSC1000 AAC -0.24 5e-08
mRNA ATF1 GDSC1000 AAC 0.19 5e-08
mRNA NOL4 GDSC1000 AAC -0.2 5e-08
mRNA ZNF354B GDSC1000 AAC 0.2 5e-08
mRNA TGM2 GDSC1000 AAC 0.21 7e-08
mRNA GDAP1 GDSC1000 AAC -0.2 7e-08
mRNA TMCC2 GDSC1000 AAC -0.19 9e-08
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