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SourcesNames Used
PharmacoGx AUY922

External IDs

Smiles: CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Pubchem: 10096043

Cell lines tested with AUY922

932 cell lines have been tested with this compound, using data from 1 dataset(s).
NB6 autonomic ganglia GDSC10001
KYSE-450 oesophagus GDSC10001
LXF-289 lung GDSC10001
KM12 large intestine GDSC10001
CAL-27 upper aerodigestive tract GDSC10001
COR-L95 lung GDSC10001
PA-1 ovary GDSC10001
SCC-4 upper aerodigestive tract GDSC10001
MY-M12 haematopoietic and lymphoid tissue GDSC10001
MKL-1-subclone-2 skin GDSC10001
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Top molecular features associated with response to AUY922

Feature TypeStandardized
Nominal ANOVA
mRNA PLAU GDSC1000 AAC 0.27 7e-11
mRNA TMEM198 GDSC1000 AAC -0.24 1e-10
mRNA INSM1 GDSC1000 AAC -0.24 1e-10
mRNA CHGA GDSC1000 AAC -0.26 2e-10
mRNA AXL GDSC1000 AAC 0.26 1e-09
mRNA SCG3 GDSC1000 AAC -0.24 2e-09
mRNA GNAO1 GDSC1000 AAC -0.22 3e-09
mRNA ANP32B GDSC1000 AAC 0.22 6e-09
mRNA SEMA6D GDSC1000 AAC -0.21 6e-09
mRNA RBMS2 GDSC1000 AAC 0.23 6e-09
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