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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA CTRPv2 pan-cancer AAC 0.18 5e-07
mRNA CTRPv2 pan-cancer AAC 0.15 3e-06
mRNA CTRPv2 pan-cancer AAC 0.15 4e-06
mRNA CTRPv2 pan-cancer AAC 0.14 8e-06
mRNA CTRPv2 pan-cancer AAC -0.16 1e-05
mRNA CTRPv2 pan-cancer AAC 0.15 2e-05
mRNA GDSC1000 pan-cancer AAC -0.14 3e-05
mRNA gCSI pan-cancer AAC -0.23 6e-05
mRNA CTRPv2 pan-cancer AAC 0.13 6e-05
mRNA gCSI pan-cancer AAC -0.21 7e-05
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