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Merck60

Synonyms

SourcesNames Used
CTRPv2Merck60
PharmacoGx Merck60

External IDs

DatabaseIdentifier
Smiles: CC(=O)Nc1ccc(cc1)C(=O)Nc2cc(ccc2N)c3cccs3

Annotated Targets

HDAC1, HDAC2

Cell lines tested with Merck60

846 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to Merck60


Feature TypeStandardized
Nominal ANOVA
mRNA MBTD1 CTRPv2 AAC 0.26 1e-13
mRNA PHF10 CTRPv2 AAC 0.2 1e-10
mRNA ZBED4 CTRPv2 AAC 0.22 3e-10
mRNA COQ8A CTRPv2 AAC 0.2 4e-09
mRNA SHPRH CTRPv2 AAC 0.19 3e-08
mRNA DNMT3A CTRPv2 AAC 0.18 4e-08
mRNA HDAC2 CTRPv2 AAC 0.17 6e-08
mRNA SNX7 CTRPv2 AAC -0.19 8e-08
mRNA STK26 CTRPv2 AAC 0.19 9e-08
mRNA CBX2 CTRPv2 AAC 0.18 1e-07
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