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masitinib

Synonyms

SourcesNames Used
GDSC1000Masitinib
CTRPv2masitinib
PharmacoGx masitinib

External IDs

DatabaseIdentifier
Smiles: CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1
Pubchem: 10074640

Annotated Targets

KIT, FGFR3, PDGFRA, PDGFRB

Cell lines tested with masitinib

1268 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
SUIT-2 pancreas GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
P3HR-1 haematopoietic and lymphoid tissue GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
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Top molecular features associated with response to masitinib


Feature TypeStandardized
Nominal ANOVA
mRNA CISH CTRPv2 AAC 0.43 8e-33
mRNA CFAP161 GDSC1000 AAC 0.32 1e-25
mRNA PIM1 CTRPv2 AAC 0.38 2e-25
mRNA CISH GDSC1000 AAC 0.32 2e-21
mRNA GFI1B GDSC1000 AAC 0.29 2e-20
mRNA OSM GDSC1000 AAC 0.32 2e-19
mRNA PRSS57 GDSC1000 AAC 0.3 4e-19
mRNA CCR6 CTRPv2 AAC 0.3 4e-18
mRNA RP11-231C18.3 CTRPv2 AAC 0.29 5e-16
mRNA GAB2 GDSC1000 AAC 0.27 1e-15
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