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LFM-A13

Synonyms

SourcesNames Used
GDSC1000LFM-A13
PharmacoGx LFM-A13

External IDs

DatabaseIdentifier
Smiles: CC(=C(C#N)C(=O)NC1=C(C=CC(=C1)Br)Br)O
Inchikey: UVSVTDVJQAJIFG-VURMDHGXSA-N
Pubchem: 54676905

Annotated Targets

BTK

Cell lines tested with LFM-A13

932 cell lines have been tested with this compound, using data from 1 dataset(s).
RPMI-6666 haematopoietic and lymphoid tissue GDSC10001
KYSE-30 oesophagus GDSC10001
Panc 02.03 pancreas GDSC10001
LOXIMVI haematopoietic and lymphoid tissue GDSC10001
MSTO-211H pleura GDSC10001
JHU-029 upper aerodigestive tract GDSC10001
CPC-N lung GDSC10001
OCI-AML2 haematopoietic and lymphoid tissue GDSC10001
ROS-50 haematopoietic and lymphoid tissue GDSC10001
GB-1 central nervous system GDSC10001
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Top molecular features associated with response to LFM-A13


Feature TypeStandardized
Nominal ANOVA
mRNA NR1H2 GDSC1000 AAC 0.18 7e-07
mRNA YIPF3 GDSC1000 AAC 0.17 1e-06
mRNA IER5L GDSC1000 AAC 0.19 2e-06
mRNA PNPLA6 GDSC1000 AAC 0.16 3e-06
mRNA NNMT GDSC1000 AAC 0.19 5e-06
mRNA ANTXR1 GDSC1000 AAC 0.18 6e-06
mRNA CUEDC1 GDSC1000 AAC 0.17 6e-06
mRNA MPP2 GDSC1000 AAC -0.15 9e-06
mRNA DACH1 GDSC1000 AAC -0.16 9e-06
mRNA RNF138 GDSC1000 AAC -0.17 1e-05
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