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lenalidomide

Synonyms

SourcesNames Used
GDSC1000, FIMMLenalidomide
PharmacoGx lenalidomide

External IDs

DatabaseIdentifier
Smiles: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
Inchikey: GOTYRUGSSMKFNF-UHFFFAOYSA-N
Pubchem: 216326

Annotated Targets

CDH5, CRBN, PTGS2, TNF, TNFSF11

Cell lines tested with lenalidomide

905 cell lines have been tested with this compound, using data from 2 dataset(s).
OV-90 ovary GDSC1000, FIMM2
ML-2 haematopoietic and lymphoid tissue GDSC1000, FIMM2
MV-4-11 haematopoietic and lymphoid tissue GDSC1000, FIMM2
MDA-MB-436 breast GDSC1000, FIMM2
RMG-I ovary GDSC1000, FIMM2
K-562 haematopoietic and lymphoid tissue GDSC1000, FIMM2
MDA-MB-231 breast GDSC1000, FIMM2
BT-549 breast GDSC1000, FIMM2
GDM-1 haematopoietic and lymphoid tissue GDSC1000, FIMM2
IGROV-1 ovary GDSC1000, FIMM2
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Top molecular features associated with response to lenalidomide


Feature TypeStandardized
Nominal ANOVA
mRNA SLC19A1 GDSC1000 AAC 0.18 5e-07
mRNA SEPT14 GDSC1000 AAC 0.17 9e-07
mRNA MORC1 GDSC1000 AAC 0.17 2e-06
mRNA KISS1R GDSC1000 AAC 0.16 2e-06
mRNA RAB36 GDSC1000 AAC 0.16 4e-06
mRNA WDR4 GDSC1000 AAC 0.16 4e-06
mRNA ANKLE1 GDSC1000 AAC 0.22 4e-06
mRNA SPATA16 GDSC1000 AAC 0.16 6e-06
mRNA CCR1 GDSC1000 AAC 0.16 7e-06
mRNA CCR3 GDSC1000 AAC 0.16 9e-06
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