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SourcesNames Used
PharmacoGx LE-135

External IDs

Smiles: CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C
Pubchem: 10410894

Annotated Targets


Cell lines tested with LE-135

828 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to LE-135

Feature TypeStandardized
Nominal ANOVA
mRNA MCOLN2 CTRPv2 AAC 0.21 4e-08
mRNA CENPF CTRPv2 AAC 0.18 6e-07
mRNA ZFAND6 CTRPv2 AAC -0.17 1e-06
mRNA XPNPEP1 CTRPv2 AAC -0.18 2e-06
mRNA FOXI3 CTRPv2 AAC 0.17 2e-06
mRNA GHRH CTRPv2 AAC 0.16 4e-06
mRNA BCLAF1 CTRPv2 AAC 0.17 5e-06
mRNA RP11-321N4.5 CTRPv2 AAC 0.16 5e-06
mRNA FAM205C CTRPv2 AAC 0.16 7e-06
mRNA EPHB1 CTRPv2 AAC 0.16 8e-06
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