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L-685458

Synonyms

SourcesNames Used
CCLE, CTRPv2L-685458
PharmacoGx L-685458

External IDs

DatabaseIdentifier
Smiles: CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OC(C)(C)C)O
Inchikey: MURCDOXDAHPNRQ-ZJKZPDEISA-N
Pubchem: 5479543

Annotated Targets

APH1A, NCSTN, PSEN1, PSENEN

Cell lines tested with L-685458

918 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CCLE, CTRPv24
SUIT-2 pancreas CCLE, CTRPv23
NCI-H520 lung CCLE, CTRPv23
NCI-H460 lung CCLE, CTRPv23
NCI-H1869 lung CCLE, CTRPv23
NCI-H1299 lung CCLE, CTRPv23
MKN74 stomach CCLE, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue CCLE, CTRPv23
KE-39 stomach CCLE, CTRPv23
IGROV-1 ovary CCLE, CTRPv23
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Top molecular features associated with response to L-685458


Feature TypeStandardized
Nominal ANOVA
mRNA FAM9A CTRPv2 AAC 0.22 3e-10
mRNA TEX13B CTRPv2 AAC 0.22 5e-10
mRNA CXCL11 CTRPv2 AAC 0.22 1e-09
mRNA DEFA6 CTRPv2 AAC 0.2 4e-08
mRNA CCDC172 CTRPv2 AAC 0.19 5e-08
mRNA AC006386.1 CTRPv2 AAC 0.19 9e-08
mRNA FABP2 CTRPv2 AAC 0.2 1e-07
mRNA ARL11 CCLE AAC 0.28 2e-07
mRNA SPCS2 CCLE AAC 0.25 3e-07
mRNA RREB1 CCLE AAC 0.25 3e-07
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