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KU-60019

Synonyms

SourcesNames Used
CTRPv2KU-60019
PharmacoGx KU-60019

External IDs

DatabaseIdentifier
Smiles: CC1CN(CC(=O)Nc2ccc3Sc4c(Cc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)CC(C)O1
Pubchem: 15953870

Annotated Targets

ATM

Cell lines tested with KU-60019

840 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to KU-60019


Feature TypeStandardized
Nominal ANOVA
mRNA TEX22 CTRPv2 AAC 0.2 1e-07
mRNA YLPM1 CTRPv2 AAC 0.18 5e-07
mRNA SMARCA4 CTRPv2 AAC 0.19 9e-07
mRNA MTA1 CTRPv2 AAC 0.16 9e-06
mRNA IKZF1 CTRPv2 AAC 0.23 1e-05
mRNA PHLDA1 CTRPv2 AAC -0.17 1e-05
mRNA TCEAL1 CTRPv2 AAC -0.15 1e-05
mRNA YY1 CTRPv2 AAC 0.16 1e-05
mRNA SF1 CTRPv2 AAC 0.17 1e-05
mRNA NDEL1 CTRPv2 AAC -0.16 2e-05
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