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KU-55933

Synonyms

SourcesNames Used
GDSC1000, CTRPv2KU-55933
PharmacoGx KU-55933

External IDs

DatabaseIdentifier
Smiles: C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4
Inchikey: XRKYMMUGXMWDAO-UHFFFAOYSA-N
Pubchem: 5278396

Annotated Targets

ATM, PRKDC

Cell lines tested with KU-55933

1246 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
NCI-H1869 lung GDSC1000, CTRPv23
IGROV-1 ovary GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
SUIT-2 pancreas GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
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Top molecular features associated with response to KU-55933


Feature TypeStandardized
Nominal ANOVA
mRNA CCR8 GDSC1000 AAC 0.19 4e-08
mRNA MAGEB3 GDSC1000 AAC 0.18 2e-07
mRNA RPS4Y2 GDSC1000 AAC 0.16 5e-06
mRNA SLC22A3 CTRPv2 AAC 0.17 7e-06
mRNA KAT2A GDSC1000 AAC 0.16 1e-05
mRNA HIST1H2BB GDSC1000 AAC 0.15 1e-05
mRNA UTS2B GDSC1000 AAC 0.15 2e-05
mRNA TEX22 CTRPv2 AAC 0.17 2e-05
mRNA CD247 GDSC1000 AAC 0.16 3e-05
mRNA DYNLL2 GDSC1000 AAC -0.15 4e-05
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