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KPT185

Synonyms

SourcesNames Used
CTRPv2KPT185
PharmacoGx KPT185

External IDs

DatabaseIdentifier
Pubchem: 53495165

Annotated Targets

XPO1

Cell lines tested with KPT185

632 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
A549 lung CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to KPT185


Feature TypeStandardized
Nominal ANOVA
mRNA MEX3A CTRPv2 AAC 0.34 6e-12
mRNA CD63 CTRPv2 AAC -0.32 9e-12
mRNA C2CD4C CTRPv2 AAC 0.25 6e-11
mRNA HNRNPA1 CTRPv2 AAC 0.28 1e-10
mRNA SEZ6 CTRPv2 AAC 0.24 3e-10
mRNA CHRNB2 CTRPv2 AAC 0.26 5e-10
mRNA PRR36 CTRPv2 AAC 0.25 6e-10
mRNA FSD1 CTRPv2 AAC 0.27 7e-10
mRNA DOT1L CTRPv2 AAC 0.28 1e-09
mRNA MFSD13A CTRPv2 AAC 0.24 1e-09
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