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Ko-143

Synonyms

SourcesNames Used
CTRPv2Ko-143
PharmacoGx Ko-143

External IDs

DatabaseIdentifier
Smiles: CC(C)CC1C2=C(CC3N1C(=O)C(NC3=O)CCC(=O)OC(C)(C)C)C4=C(N2)C=C(C=C4)OC
Inchikey: NXNRAECHCJZNRF-JBACZVJFSA-N
Pubchem: 10322450

Annotated Targets

ABCB1, ABCC1, ABCG2

Cell lines tested with Ko-143

835 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to Ko-143


Feature TypeStandardized
Nominal ANOVA
mRNA TEX13B CTRPv2 AAC 0.39 9e-30
mRNA FAM9A CTRPv2 AAC 0.38 1e-28
mRNA CCDC172 CTRPv2 AAC 0.33 6e-21
mRNA FAM9B CTRPv2 AAC 0.28 1e-15
mRNA VCX3A CTRPv2 AAC 0.27 6e-15
mRNA MAGEB16 CTRPv2 AAC 0.27 2e-14
mRNA VCX CTRPv2 AAC 0.27 2e-14
mRNA VCX2 CTRPv2 AAC 0.27 3e-14
mRNA RP13-347D8.7 CTRPv2 AAC 0.26 9e-14
mRNA AC006386.1 CTRPv2 AAC 0.26 2e-13
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