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ISOX

Synonyms

SourcesNames Used
CTRPv2ISOX
PharmacoGx ISOX

External IDs

DatabaseIdentifier
Smiles: CC(C)(C)OC(=O)Nc1ccc(cc1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO

Annotated Targets

HDAC6

Cell lines tested with ISOX

830 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to ISOX


Feature TypeStandardized
Nominal ANOVA
mRNA MBTD1 CTRPv2 AAC 0.25 1e-11
mRNA MYOF CTRPv2 AAC -0.24 2e-11
mRNA S100A6 CTRPv2 AAC -0.23 4e-11
mRNA CHD4 CTRPv2 AAC 0.22 4e-11
mRNA MEX3A CTRPv2 AAC 0.25 1e-10
mRNA CBX2 CTRPv2 AAC 0.23 2e-10
mRNA DNMT3A CTRPv2 AAC 0.21 6e-10
mRNA ZBED4 CTRPv2 AAC 0.23 7e-10
mRNA CIB1 CTRPv2 AAC -0.2 2e-09
mRNA MARCKSL1 CTRPv2 AAC 0.19 2e-09
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