1. Home/
  2. Compounds/
  3. ibrutinib

ibrutinib

Synonyms

SourcesNames Used
CTRPv2ibrutinib
PharmacoGx ibrutinib

External IDs

DatabaseIdentifier
Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C
Pubchem: 24821094

Annotated Targets

BLK, BMX, BTK

Cell lines tested with ibrutinib

597 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
A549 lung CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
Download CSV
Download Data as CSV

Top molecular features associated with response to ibrutinib


Feature TypeStandardized
Nominal ANOVA
mRNA ERBB2 CTRPv2 AAC 0.29 7e-11
mRNA SMIM14 CTRPv2 AAC 0.26 7e-10
mRNA CYB561A3 CTRPv2 AAC 0.26 8e-10
mRNA NCOA3 CTRPv2 AAC 0.25 1e-09
mRNA BCL7A CTRPv2 AAC 0.28 1e-09
mRNA STARD3 CTRPv2 AAC 0.27 2e-09
mRNA MS4A1 CTRPv2 AAC 0.26 2e-09
mRNA ZNF296 CTRPv2 AAC 0.3 4e-09
mRNA TRAF4 CTRPv2 AAC 0.25 1e-08
mRNA HLA-DMB CTRPv2 AAC 0.24 2e-08
Download CSV