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GW843682X

Synonyms

SourcesNames Used
GDSC1000GW843682X
CTRPv2GW-843682X
PharmacoGx GW843682X

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC
Inchikey: JSKUWFIZUALZLX-UHFFFAOYSA-N
Pubchem: 9826308

Annotated Targets

PLK1, PLK3

Cell lines tested with GW843682X

1027 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to GW843682X


Feature TypeStandardized
Nominal ANOVA
mRNA PRPF38A CTRPv2 AAC 0.27 8e-13
mRNA ARHGAP19 CTRPv2 AAC 0.3 1e-12
mRNA GMEB1 CTRPv2 AAC 0.26 3e-12
mRNA KLHL23 CTRPv2 AAC 0.27 7e-12
mRNA POLR2D CTRPv2 AAC 0.25 1e-11
mRNA ORC1 CTRPv2 AAC 0.26 2e-11
mRNA MCM2 CTRPv2 AAC 0.26 2e-11
mRNA TUBGCP4 CTRPv2 AAC 0.24 2e-11
mRNA ARHGAP19-SLIT1 CTRPv2 AAC 0.27 3e-11
mRNA RBM10 CTRPv2 AAC 0.24 6e-11
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