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GW 441756

Synonyms

SourcesNames Used
GDSC1000GW 441756
PharmacoGx GW 441756

External IDs

DatabaseIdentifier
Smiles: Cn1cc(C=C2C(=O)Nc3cccnc23)c4ccccc14
Pubchem: 9943465

Annotated Targets

NTRK1

Cell lines tested with GW 441756

895 cell lines have been tested with this compound, using data from 1 dataset(s).
NCI-H1993 lung GDSC10001
RO82-W-1 thyroid GDSC10001
MZ2-MEL skin GDSC10001
KS-1 central nervous system GDSC10001
LIM1215 large intestine GDSC10001
201T lung GDSC10001
OV7 ovary GDSC10001
IOSE-364- ovary GDSC10001
KURAMOCHI ovary GDSC10001
LXF-289 lung GDSC10001
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Top molecular features associated with response to GW 441756


Feature TypeStandardized
Nominal ANOVA
mRNA TAGLN3 GDSC1000 AAC -0.17 2e-05
mRNA DNAJC21 GDSC1000 AAC 0.15 3e-05
mRNA CCT5 GDSC1000 AAC 0.15 3e-05
mRNA FAM45A GDSC1000 AAC 0.14 5e-05
mRNA SNX17 GDSC1000 AAC 0.14 5e-05
mRNA IDE GDSC1000 AAC 0.14 5e-05
mRNA S100A11 GDSC1000 AAC 0.17 5e-05
mRNA SMIM8 GDSC1000 AAC -0.16 5e-05
mRNA ENO2 GDSC1000 AAC -0.15 6e-05
mRNA CDK5R1 GDSC1000 AAC -0.15 7e-05
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