1. Home/
  2. Compounds/
  3. GSK690693

GSK690693

Synonyms

SourcesNames Used
GDSC1000GSK690693
PharmacoGx GSK690693

External IDs

DatabaseIdentifier
Smiles: CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
Inchikey: KGPGFQWBCSZGEL-ZDUSSCGKSA-N
Pubchem: 16725726

Annotated Targets

AKT2, PRKACB, AKT1, AKT3, PAK4, PAK6, PRKCQ, PRKG1, PRKX

Cell lines tested with GSK690693

980 cell lines have been tested with this compound, using data from 1 dataset(s).
GDM-1 haematopoietic and lymphoid tissue GDSC10001
NCI-H2087 lung GDSC10001
MDA-MB-453 breast GDSC10001
PFSK-1 central nervous system GDSC10001
MDA-MB-468 breast GDSC10001
KMH-2 thyroid GDSC10001
MOLT-13 haematopoietic and lymphoid tissue GDSC10001
BFTC-905 urinary tract GDSC10001
KURAMOCHI ovary GDSC10001
KS-1 central nervous system GDSC10001
Download CSV

Tissues tested with GSK690693

35 tissues have been tested with this compound, using data from 1 dataset(s).
neuroblastomaGDSC10001
adrenal glandGDSC10001
placentaGDSC10001
miscGDSC10001
small intestineGDSC10001
Download CSV
Download Data as CSV

Top molecular features associated with response to GSK690693


Feature TypeStandardized
Nominal ANOVA
mRNA ESR2 GDSC1000 AAC 0.23 5e-12
mRNA FUCA2 GDSC1000 AAC -0.25 7e-12
mRNA CD151 GDSC1000 AAC -0.28 9e-12
mRNA TNFRSF12A GDSC1000 AAC -0.31 1e-11
mRNA DTX1 GDSC1000 AAC 0.24 1e-11
mRNA SEC11A GDSC1000 AAC -0.21 1e-11
mRNA GRAP GDSC1000 AAC 0.27 1e-11
mRNA TJP1 GDSC1000 AAC -0.41 1e-11
mRNA CD19 GDSC1000 AAC 0.25 1e-11
mRNA SBK1 GDSC1000 AAC 0.25 2e-11
Download CSV