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GSK690693

Synonyms

SourcesNames Used
GDSC1000GSK690693
PharmacoGx GSK690693

External IDs

DatabaseIdentifier
Smiles: CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
Inchikey: KGPGFQWBCSZGEL-ZDUSSCGKSA-N
Pubchem: 16725726

Annotated Targets

AKT2, PRKACB, AKT1, AKT3, PAK4, PAK6, PRKCQ, PRKG1, PRKX

Cell lines tested with GSK690693

980 cell lines have been tested with this compound, using data from 1 dataset(s).
GDM-1 haematopoietic and lymphoid tissue GDSC10001
NCI-H2087 lung GDSC10001
MDA-MB-453 breast GDSC10001
PFSK-1 central nervous system GDSC10001
MDA-MB-468 breast GDSC10001
KMH-2 thyroid GDSC10001
MOLT-13 haematopoietic and lymphoid tissue GDSC10001
BFTC-905 urinary tract GDSC10001
KURAMOCHI ovary GDSC10001
KS-1 central nervous system GDSC10001
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Tissues tested with GSK690693

35 tissues have been tested with this compound, using data from 1 dataset(s).
neuroblastomaGDSC10001
adrenal glandGDSC10001
placentaGDSC10001
miscGDSC10001
small intestineGDSC10001
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Top molecular features associated with response to GSK690693


Feature TypeStandardized
Nominal ANOVA
mRNA FAM189B GDSC1000 AAC 3.8e-05 1
mRNA FGF12 GDSC1000 AAC 2.2e-05 1
mRNA SORBS1 GDSC1000 AAC 2e-05 1
mRNA CPO GDSC1000 AAC -1.7e-05 1
mRNA RPL38 GDSC1000 AAC -1.7e-05 1
mRNA PRDX1 GDSC1000 AAC -1.4e-05 1
mRNA PDCD7 GDSC1000 AAC -5.9e-06 1
mRNA CYP4Z1 GDSC1000 AAC 5e-06 1
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