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GSK690693

Synonyms

SourcesNames Used
GDSC1000GSK690693
PharmacoGx GSK690693

External IDs

DatabaseIdentifier
Smiles: CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
Inchikey: KGPGFQWBCSZGEL-ZDUSSCGKSA-N
Pubchem: 16725726

Annotated Targets

AKT2, PRKACB, AKT1, AKT3, PAK4, PAK6, PRKCQ, PRKG1, PRKX

Cell lines tested with GSK690693

980 cell lines have been tested with this compound, using data from 1 dataset(s).
SW13 adrenal gland GDSC10001
SK-N-FI autonomic ganglia GDSC10001
NB69 autonomic ganglia GDSC10001
SK-N-AS autonomic ganglia GDSC10001
NB7 autonomic ganglia GDSC10001
NB10 autonomic ganglia GDSC10001
BE2-M17 autonomic ganglia GDSC10001
NBsusSR autonomic ganglia GDSC10001
IMR-5 autonomic ganglia GDSC10001
KP-N-YS autonomic ganglia GDSC10001
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Top molecular features associated with response to GSK690693


Feature TypeStandardized
Nominal ANOVA
mRNA ESR2 GDSC1000 AAC 0.23 5e-12
mRNA FUCA2 GDSC1000 AAC -0.25 7e-12
mRNA CD151 GDSC1000 AAC -0.28 9e-12
mRNA TNFRSF12A GDSC1000 AAC -0.31 1e-11
mRNA DTX1 GDSC1000 AAC 0.24 1e-11
mRNA SEC11A GDSC1000 AAC -0.21 1e-11
mRNA GRAP GDSC1000 AAC 0.27 1e-11
mRNA TJP1 GDSC1000 AAC -0.41 1e-11
mRNA CD19 GDSC1000 AAC 0.25 1e-11
mRNA SBK1 GDSC1000 AAC 0.25 2e-11
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