1. Home/
  2. Compounds/
  3. GSK690693

GSK690693

Synonyms

SourcesNames Used
GDSC1000GSK690693
PharmacoGx GSK690693

External IDs

DatabaseIdentifier
Smiles: CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
Inchikey: KGPGFQWBCSZGEL-ZDUSSCGKSA-N
Pubchem: 16725726

Annotated Targets

AKT2, PRKACB, AKT1, AKT3, PAK4, PAK6, PRKCQ, PRKG1, PRKX

Cell lines tested with GSK690693

980 cell lines have been tested with this compound, using data from 1 dataset(s).
HDQ-P1 breast GDSC10001
BT-474 breast GDSC10001
A427 lung GDSC10001
KMS-12-BM haematopoietic and lymphoid tissue GDSC10001
TOV-21G ovary GDSC10001
SK-N-FI autonomic ganglia GDSC10001
CMK haematopoietic and lymphoid tissue GDSC10001
PCI-38 head and neck GDSC10001
BB65-RCC kidney GDSC10001
NB69 autonomic ganglia GDSC10001
Download CSV
Download Data as CSV

Top molecular features associated with response to GSK690693


Feature TypeStandardized
Nominal ANOVA
mRNA ESR2 GDSC1000 AAC 0.23 5e-12
mRNA FUCA2 GDSC1000 AAC -0.25 7e-12
mRNA CD151 GDSC1000 AAC -0.28 9e-12
mRNA TNFRSF12A GDSC1000 AAC -0.31 1e-11
mRNA DTX1 GDSC1000 AAC 0.24 1e-11
mRNA SEC11A GDSC1000 AAC -0.21 1e-11
mRNA GRAP GDSC1000 AAC 0.27 1e-11
mRNA TJP1 GDSC1000 AAC -0.41 1e-11
mRNA CD19 GDSC1000 AAC 0.25 1e-11
mRNA SBK1 GDSC1000 AAC 0.25 2e-11
Download CSV