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GSK690693

Synonyms

SourcesNames Used
GDSC1000GSK690693
PharmacoGx GSK690693

External IDs

DatabaseIdentifier
Smiles: CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
Inchikey: KGPGFQWBCSZGEL-ZDUSSCGKSA-N
Pubchem: 16725726

Annotated Targets

AKT2, PRKACB, AKT1, AKT3, PAK4, PAK6, PRKCQ, PRKG1, PRKX

Cell lines tested with GSK690693

980 cell lines have been tested with this compound, using data from 1 dataset(s).
HDQ-P1 breast GDSC10001
BT-474 breast GDSC10001
A427 lung GDSC10001
KMS-12-BM haematopoietic and lymphoid tissue GDSC10001
TOV-21G ovary GDSC10001
SK-N-FI autonomic ganglia GDSC10001
CMK haematopoietic and lymphoid tissue GDSC10001
PCI-38 head and neck GDSC10001
BB65-RCC kidney GDSC10001
NB69 autonomic ganglia GDSC10001
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Top molecular features associated with response to GSK690693


Feature TypeStandardized
Nominal ANOVA
mRNA FAM189B GDSC1000 AAC 3.8e-05 1
mRNA FGF12 GDSC1000 AAC 2.2e-05 1
mRNA SORBS1 GDSC1000 AAC 2e-05 1
mRNA CPO GDSC1000 AAC -1.7e-05 1
mRNA RPL38 GDSC1000 AAC -1.7e-05 1
mRNA PRDX1 GDSC1000 AAC -1.4e-05 1
mRNA PDCD7 GDSC1000 AAC -5.9e-06 1
mRNA CYP4Z1 GDSC1000 AAC 5e-06 1
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