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GSK429286A

Synonyms

SourcesNames Used
GDSC1000GSK429286A
PharmacoGx GSK429286A

External IDs

DatabaseIdentifier
Smiles: CC1=C(C(CC(=O)N1)c1ccc(cc1)C(F)(F)F)C(=O)Nc1cc2cn[nH]c2cc1F
Pubchem: 11373846

Annotated Targets

ROCK1

Cell lines tested with GSK429286A

984 cell lines have been tested with this compound, using data from 1 dataset(s).
NCI-H2405 lung GDSC10001
HCC1806 breast GDSC10001
OVCAR-4 ovary GDSC10001
BB30-HNC upper aerodigestive tract GDSC10001
BB49-HNC upper aerodigestive tract GDSC10001
SK-MEL-1 skin GDSC10001
AMO-1 haematopoietic and lymphoid tissue GDSC10001
L-363 haematopoietic and lymphoid tissue GDSC10001
A2058 skin GDSC10001
SF268 central nervous system GDSC10001
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Top molecular features associated with response to GSK429286A


Feature TypeStandardized
Nominal ANOVA
mRNA WASF1 GDSC1000 AAC 0.21 2e-08
mRNA CEP170 GDSC1000 AAC 0.2 6e-08
mRNA ZNF445 GDSC1000 AAC 0.2 7e-08
mRNA PCM1 GDSC1000 AAC 0.19 8e-08
mRNA RAB17 GDSC1000 AAC -0.21 1e-07
mRNA SDC4 GDSC1000 AAC -0.24 1e-07
mRNA RBM47 GDSC1000 AAC -0.2 2e-07
mRNA FAM216A GDSC1000 AAC 0.19 2e-07
mRNA CEP57L1 GDSC1000 AAC 0.17 3e-07
mRNA MDH1B GDSC1000 AAC 0.17 3e-07
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