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GSK1059615

Synonyms

SourcesNames Used
GRAY, CTRPv2GSK1059615
PharmacoGx GSK1059615

External IDs

DatabaseIdentifier
Smiles: C1=CC2=NC=CC(=C2C=C1C=C3C(=O)NC(=O)S3)C4=CC=NC=C4
Inchikey: QDITZBLZQQZVEE-YBEGLDIGSA-N
Pubchem: 23582824

Annotated Targets

PIK3CD, PIK3CG, MTOR, PIK3CA, PIK3CB

Cell lines tested with GSK1059615

615 cell lines have been tested with this compound, using data from 2 dataset(s).
HCC2185 breast GRAY9
MDA-MB-361 breast GRAY, CTRPv28
MDA-MB-468 breast GRAY, CTRPv26
HCC1419 breast GRAY, CTRPv26
HCC1954 breast GRAY5
Hs-578-T breast GRAY, CTRPv25
SUM 159PT breast GRAY5
SUM 1315M02 breast GRAY5
BT-549 breast GRAY, CTRPv24
ZR-75-1 breast GRAY, CTRPv24
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Top molecular features associated with response to GSK1059615


Feature TypeStandardized
Nominal ANOVA
mRNA DAXX CTRPv2 AAC 0.25 2e-07
mRNA AC141272.1 CTRPv2 AAC 0.23 2e-07
mRNA BMF CTRPv2 AAC 0.24 2e-07
mRNA SHKBP1 CTRPv2 AAC 0.26 2e-07
mRNA NLRP7 CTRPv2 AAC 0.22 2e-07
mRNA CYB561A3 CTRPv2 AAC 0.24 2e-07
mRNA CXCR5 CTRPv2 AAC 0.22 5e-07
mRNA ALDH5A1 CTRPv2 AAC 0.24 6e-07
mRNA STRA8 CTRPv2 AAC 0.22 6e-07
mRNA SPIB CTRPv2 AAC 0.22 3e-06
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