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GSK-650394

Synonyms

SourcesNames Used
GDSC1000GSK-650394
GRAYGSK650394
PharmacoGx GSK-650394

External IDs

DatabaseIdentifier
Smiles: C1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=NC=C(C=C34)C5=CC=CC=C5)C(=O)O
Inchikey: WVSBGSNVCDAMCF-UHFFFAOYSA-N
Pubchem: 25022668

Annotated Targets

SGK1, SGK2

Cell lines tested with GSK-650394

955 cell lines have been tested with this compound, using data from 2 dataset(s).
BT-474 breast GDSC1000, GRAY4
MDA-MB-415 breast GDSC1000, GRAY3
MDA-MB-361 breast GDSC1000, GRAY3
MDA-MB-231 breast GDSC1000, GRAY3
HCC70 breast GDSC1000, GRAY3
MDA-MB-134-VI breast GDSC1000, GRAY3
HCC1395 breast GDSC1000, GRAY3
HCC1569 breast GDSC1000, GRAY3
HCC2185 breast GRAY2
SUM 1315M02 breast GRAY2
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Top molecular features associated with response to GSK-650394


Feature TypeStandardized
Nominal ANOVA
mRNA TIFAB GDSC1000 AAC 0.22 5e-11
mRNA IARS GDSC1000 AAC 0.22 2e-10
mRNA PPP1R27 GDSC1000 AAC 0.21 7e-10
mRNA B3GNTL1 GDSC1000 AAC 0.22 9e-10
mRNA PRSS57 GDSC1000 AAC 0.23 1e-09
mRNA LARS GDSC1000 AAC 0.22 3e-09
mRNA C10orf2 GDSC1000 AAC 0.23 6e-09
mRNA ADAT2 GDSC1000 AAC 0.23 6e-09
mRNA KIF3B GDSC1000 AAC -0.22 8e-09
mRNA NPM3 GDSC1000 AAC 0.2 1e-08
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