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gossypol

Synonyms

SourcesNames Used
CTRPv2gossypol
PharmacoGx gossypol

External IDs

DatabaseIdentifier
Smiles: CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C
Inchikey: QBKSWRVVCFFDOT-UHFFFAOYSA-N
Pubchem: 3503

Annotated Targets

BCL2, BCL2L1, LDHA, LDHB, LDHC

Cell lines tested with gossypol

798 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to gossypol


Feature TypeStandardized
Nominal ANOVA
mRNA HNRNPU CTRPv2 AAC 0.25 1e-10
mRNA RCC2 CTRPv2 AAC 0.24 6e-09
mRNA SFPQ CTRPv2 AAC 0.23 7e-09
mRNA INTS7 CTRPv2 AAC 0.22 2e-08
mRNA ANKRD17 CTRPv2 AAC 0.21 3e-08
mRNA BEND3 CTRPv2 AAC 0.22 5e-08
mRNA RIOK1 CTRPv2 AAC 0.21 6e-08
mRNA PRPF38A CTRPv2 AAC 0.22 9e-08
mRNA RBM25 CTRPv2 AAC 0.2 1e-07
mRNA RP11-159D12.5 CTRPv2 AAC 0.21 1e-07
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