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SourcesNames Used
PharmacoGx GNF-2

External IDs

Smiles: C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
Pubchem: 5311510

Annotated Targets


Cell lines tested with GNF-2

426 cell lines have been tested with this compound, using data from 1 dataset(s).
DOHH-2 haematopoietic and lymphoid tissue GDSC10001
VCaP prostate GDSC10001
HCC2218 breast GDSC10001
ES-2 ovary GDSC10001
ACN autonomic ganglia GDSC10001
REH haematopoietic and lymphoid tissue GDSC10001
RS4;11 haematopoietic and lymphoid tissue GDSC10001
CHP-126 autonomic ganglia GDSC10001
KARPAS-45 haematopoietic and lymphoid tissue GDSC10001
TGW autonomic ganglia GDSC10001
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Top molecular features associated with response to GNF-2

Feature TypeStandardized
Nominal ANOVA
mRNA GAB2 GDSC1000 AAC 0.32 6e-10
mRNA CISH GDSC1000 AAC 0.29 7e-08
mRNA CFAP161 GDSC1000 AAC 0.26 2e-07
mRNA PRELP GDSC1000 AAC 0.25 5e-07
mRNA ST8SIA6 GDSC1000 AAC 0.25 6e-07
mRNA MED15 GDSC1000 AAC 0.29 6e-07
mRNA OMD GDSC1000 AAC 0.24 9e-07
mRNA MUC4 GDSC1000 AAC 0.27 2e-06
mRNA TBXA2R GDSC1000 AAC 0.24 2e-06
mRNA ITGA5 GDSC1000 AAC 0.27 3e-06
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