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GMX-1778

Synonyms

SourcesNames Used
CTRPv2GMX-1778
PharmacoGx GMX-1778

External IDs

DatabaseIdentifier
Smiles: Clc1ccc(OCCCCCCN=C(NC#N)Nc2ccncc2)cc1

Annotated Targets

NAMPT

Cell lines tested with GMX-1778

842 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to GMX-1778


Feature TypeStandardized
Nominal ANOVA
mRNA ELAVL1 CTRPv2 AAC 0.32 1e-16
mRNA HSF2 CTRPv2 AAC 0.28 9e-15
mRNA POU2F1 CTRPv2 AAC 0.3 2e-14
mRNA ZNF738 CTRPv2 AAC 0.27 3e-14
mRNA HNRNPA1 CTRPv2 AAC 0.3 5e-14
mRNA ZKSCAN2 CTRPv2 AAC 0.29 1e-13
mRNA ZMYM3 CTRPv2 AAC 0.28 2e-13
mRNA KLHL23 CTRPv2 AAC 0.28 2e-13
mRNA KHDRBS1 CTRPv2 AAC 0.27 3e-13
mRNA SP4 CTRPv2 AAC 0.26 3e-13
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