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Gemcitabine

Synonyms

SourcesNames Used
GDSC1000, GRAYGemcitabine
gCSI, CTRPv2gemcitabine
PharmacoGx Gemcitabine

External IDs

DatabaseIdentifier
Smiles: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl
Inchikey: OKKDEIYWILRZIA-UHFFFAOYSA-N
Pubchem: 356653

Annotated Targets

CMPK1, RRM1, RRM2, TYMS

Cell lines tested with Gemcitabine

1266 cell lines have been tested with this compound, using data from 4 dataset(s).
HCC38 breast GDSC1000, gCSI, GRAY, CTRPv28
BT-549 breast gCSI, GRAY, CTRPv27
MDA-MB-468 breast GDSC1000, gCSI, GRAY, CTRPv27
MDA-MB-453 breast GDSC1000, gCSI, GRAY, CTRPv27
HCC1395 breast GDSC1000, GRAY, CTRPv27
MDA-MB-436 breast GDSC1000, gCSI, GRAY7
HCC1419 breast GDSC1000, gCSI, GRAY, CTRPv27
SK-BR-3 breast gCSI, GRAY, CTRPv26
UACC-893 breast GDSC1000, GRAY6
Hs-578-T breast GDSC1000, gCSI, GRAY, CTRPv26
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Top molecular features associated with response to Gemcitabine


Feature TypeStandardized
Nominal ANOVA
mRNA SLFN11 GDSC1000 AAC 0.36 7e-22
mRNA SLFN11 CTRPv2 AAC 0.3 2e-18
mRNA SLFN11 gCSI AAC 0.42 2e-14
mRNA CPSF6 CTRPv2 AAC 0.27 1e-12
mRNA ANP32B GDSC1000 AAC 0.27 2e-12
mRNA HNRNPA1 CTRPv2 AAC 0.27 2e-12
mRNA SFPQ CTRPv2 AAC 0.25 3e-12
mRNA SAFB CTRPv2 AAC 0.25 1e-11
mRNA SBDS CTRPv2 AAC -0.24 2e-11
mRNA PROSER1 CTRPv2 AAC 0.26 2e-11
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