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GDC-0879

Synonyms

SourcesNames Used
CTRPv2GDC-0879
PharmacoGx GDC-0879

External IDs

DatabaseIdentifier
Smiles: OCCn1cc(c(n1)-c1ccncc1)-c1ccc2c(CCC2=N/O)c1
Pubchem: 11717001

Annotated Targets

BRAF

Cell lines tested with GDC-0879

821 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to GDC-0879


Feature TypeStandardized
Nominal ANOVA
mRNA SPRY4 CTRPv2 AAC 0.45 8e-35
mRNA SPRED1 CTRPv2 AAC 0.38 2e-20
mRNA TRIM51 CTRPv2 AAC 0.34 9e-19
mRNA NFATC2 CTRPv2 AAC 0.36 2e-18
mRNA INPP5F CTRPv2 AAC 0.39 3e-18
mRNA LYST CTRPv2 AAC 0.31 2e-17
mRNA SH2B3 CTRPv2 AAC 0.33 5e-17
mRNA GAS7 CTRPv2 AAC 0.33 2e-16
mRNA PHLDA2 CTRPv2 AAC 0.32 2e-16
mRNA APOD CTRPv2 AAC 0.28 2e-15
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