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SourcesNames Used
PharmacoGx FTI-277

External IDs

Smiles: COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Pubchem: 3005532

Cell lines tested with FTI-277

941 cell lines have been tested with this compound, using data from 1 dataset(s).
RC-K8 haematopoietic and lymphoid tissue GDSC10001
SW48 large intestine GDSC10001
G-401 soft tissue GDSC10001
SW756 cervix GDSC10001
ESS-1 endometrium GDSC10001
GCIY stomach GDSC10001
LOU-NH91 lung GDSC10001
U-2-OS bone GDSC10001
SW962 vulva GDSC10001
8-MG-BA central nervous system GDSC10001
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Top molecular features associated with response to FTI-277

Feature TypeStandardized
Nominal ANOVA
mRNA TNFRSF12A GDSC1000 AAC 0.26 9e-08
mRNA ZFAND3 GDSC1000 AAC 0.18 3e-07
mRNA ITGA3 GDSC1000 AAC 0.21 5e-07
mRNA PHLDA1 GDSC1000 AAC 0.21 7e-07
mRNA ABLIM3 GDSC1000 AAC 0.18 7e-07
mRNA VEGFC GDSC1000 AAC 0.2 1e-06
mRNA ATAD5 GDSC1000 AAC -0.18 1e-06
mRNA C16orf72 GDSC1000 AAC 0.16 1e-06
mRNA GPC1 GDSC1000 AAC 0.2 2e-06
mRNA SERTAD1 GDSC1000 AAC 0.17 3e-06
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