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foretinib

Synonyms

SourcesNames Used
GDSC1000Foretinib
CTRPv2foretinib
PharmacoGx foretinib

External IDs

DatabaseIdentifier
Smiles: COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
Inchikey: CXQHYVUVSFXTMY-UHFFFAOYSA-N
Pubchem: 42642645

Annotated Targets

MET, KIT, TEK, FLT1, FLT4, KDR

Cell lines tested with foretinib

1276 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
NCI-H520 lung GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
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Top molecular features associated with response to foretinib


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS57 CTRPv2 AAC 0.3 2e-18
mRNA GOLGA8M CTRPv2 AAC 0.27 1e-15
mRNA GMFG CTRPv2 AAC 0.35 5e-13
mRNA GOLGA8J CTRPv2 AAC 0.24 4e-12
mRNA TIFAB CTRPv2 AAC 0.23 8e-12
mRNA DCANP1 CTRPv2 AAC 0.23 2e-11
mRNA PLPPR3 CTRPv2 AAC 0.23 6e-11
mRNA MYB CTRPv2 AAC 0.29 9e-11
mRNA SPN CTRPv2 AAC 0.3 1e-10
mRNA WASF1 GDSC1000 AAC 0.23 1e-10
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