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SourcesNames Used
PharmacoGx AM-580

External IDs

Smiles: CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Pubchem: 2126

Annotated Targets


Cell lines tested with AM-580

805 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to AM-580

Feature TypeStandardized
Nominal ANOVA
mRNA ITGAL CTRPv2 AAC 0.28 1e-11
mRNA OR2B11 CTRPv2 AAC 0.24 5e-11
mRNA STMND1 CTRPv2 AAC 0.22 3e-10
mRNA ISL2 CTRPv2 AAC 0.24 3e-10
mRNA TIFAB CTRPv2 AAC 0.22 8e-10
mRNA RPRML CTRPv2 AAC 0.22 2e-09
mRNA DCANP1 CTRPv2 AAC 0.22 2e-09
mRNA WFIKKN2 CTRPv2 AAC 0.21 8e-09
mRNA VASH1 CTRPv2 AAC 0.21 1e-08
mRNA LAMP5 CTRPv2 AAC 0.2 5e-08
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