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alvocidib

Synonyms

SourcesNames Used
CTRPv2alvocidib
PharmacoGx alvocidib

External IDs

DatabaseIdentifier
Smiles: CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
Pubchem: 5287969

Annotated Targets

CDK4, CDK2, CDK6, CDK1, CDK5, CDK7, CDK8, CDK9, EGFR, PYGM

Cell lines tested with alvocidib

440 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
YAMATO N/A CTRPv21
TTC709 N/A CTRPv21
TM87-16 N/A CTRPv21
SYO1 N/A CTRPv21
SW982 soft tissue CTRPv21
BT16 N/A CTRPv21
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Top molecular features associated with response to alvocidib


Feature TypeStandardized
Nominal ANOVA
mRNA LRRN4CL CTRPv2 AAC -0.27 2e-08
mRNA LTBP2 CTRPv2 AAC -0.28 2e-08
mRNA PODN CTRPv2 AAC -0.27 2e-08
mRNA LMNA CTRPv2 AAC -0.31 5e-08
mRNA FGF7 CTRPv2 AAC -0.27 5e-08
mRNA RAB11FIP5 CTRPv2 AAC -0.3 6e-08
mRNA TIMP2 CTRPv2 AAC -0.32 8e-08
mRNA ITGBL1 CTRPv2 AAC -0.26 9e-08
mRNA CUEDC1 CTRPv2 AAC -0.3 9e-08
mRNA LPAR1 CTRPv2 AAC -0.27 1e-07
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