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alvocidib

Synonyms

SourcesNames Used
CTRPv2alvocidib
PharmacoGx alvocidib

External IDs

DatabaseIdentifier
Smiles: CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
Pubchem: 5287969

Annotated Targets

CDK4, CDK2, CDK6, CDK1, CDK5, CDK7, CDK8, CDK9, EGFR, PYGM

Cell lines tested with alvocidib

440 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
YAMATO N/A CTRPv21
TTC709 N/A CTRPv21
TM87-16 N/A CTRPv21
SYO1 N/A CTRPv21
SW982 soft tissue CTRPv21
BT16 N/A CTRPv21
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Top molecular features associated with response to alvocidib


Feature TypeStandardized
Nominal ANOVA
mRNA NME3 CTRPv2 AAC 3.5e-05 1
mRNA EPHA1 CTRPv2 AAC 3.2e-05 1
mRNA MMRN1 CTRPv2 AAC -1.7e-05 1
mRNA PHPT1 CTRPv2 AAC 1.5e-05 1
mRNA MAGEA8 CTRPv2 AAC 1.2e-05 1
mRNA GABBR1 CTRPv2 AAC -1.2e-06 1
mRNA FAM89B CTRPv2 AAC 2.5e-07 1
mRNA SAT2 CTRPv2 AAC -1.9e-07 1
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