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EX-527

Synonyms

SourcesNames Used
GDSC1000, CTRPv2EX-527
PharmacoGx EX-527

External IDs

DatabaseIdentifier
Smiles: C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
Inchikey: FUZYTVDVLBBXDL-UHFFFAOYSA-N
Pubchem: 5113032

Annotated Targets

SIRT1

Cell lines tested with EX-527

1261 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
DU-145 prostate GDSC1000, CTRPv23
SUIT-2 pancreas GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
A375 skin GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
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Top molecular features associated with response to EX-527


Feature TypeStandardized
Nominal ANOVA
mRNA STMN4 CTRPv2 AAC 0.37 3e-16
mRNA SLC26A5 CTRPv2 AAC 0.29 1e-14
mRNA GRM7 CTRPv2 AAC 0.31 6e-14
mRNA STMN2 CTRPv2 AAC 0.34 2e-11
mRNA CEP44 CTRPv2 AAC 0.34 2e-11
mRNA KCNJ9 CTRPv2 AAC 0.28 1e-10
mRNA AC018867.1 CTRPv2 AAC 0.24 1e-10
mRNA HPCAL4 CTRPv2 AAC 0.26 2e-10
mRNA GPC2 CTRPv2 AAC 0.3 1e-09
mRNA AC009491.1 CTRPv2 AAC 0.23 2e-09
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