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erastin

Synonyms

SourcesNames Used
CTRPv2erastin
PharmacoGx erastin

External IDs

DatabaseIdentifier
Smiles: CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl
Inchikey: BKQFRNYHFIQEKN-UHFFFAOYSA-N
Pubchem: 11214940

Annotated Targets

VDAC2, SLC7A11, VDAC1

Cell lines tested with erastin

844 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to erastin


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM214 CTRPv2 AAC -0.24 5e-12
mRNA WASF1 CTRPv2 AAC 0.25 1e-10
mRNA NQO1 CTRPv2 AAC -0.24 1e-10
mRNA BCL7A CTRPv2 AAC 0.23 6e-10
mRNA GJC1 CTRPv2 AAC 0.24 1e-09
mRNA LRPAP1 CTRPv2 AAC -0.21 2e-09
mRNA HNRNPA1L2 CTRPv2 AAC 0.25 2e-09
mRNA SLC7A11 CTRPv2 AAC -0.21 5e-09
mRNA MYDGF CTRPv2 AAC -0.2 2e-08
mRNA RPL6 CTRPv2 AAC 0.21 2e-08
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