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Epothilone B

Synonyms

SourcesNames Used
GDSC1000Epothilone B
FIMMPatupilone
PharmacoGx Epothilone B

External IDs

DatabaseIdentifier
Pubchem: 448013

Annotated Targets

TUBA1A, TUBA1B, TUBA1C, TUBA3C, TUBA4A, TUBA8, TUBB, TUBB1, TUBB3, TUBB4A, TUBB4B

Cell lines tested with Epothilone B

940 cell lines have been tested with this compound, using data from 2 dataset(s).
CAL-148 breast GDSC1000, FIMM2
CAL-85-1 breast GDSC1000, FIMM2
MDA-MB-231 breast GDSC1000, FIMM2
MV-4-11 haematopoietic and lymphoid tissue GDSC1000, FIMM2
BT-474 breast GDSC1000, FIMM2
HCC1143 breast GDSC1000, FIMM2
ML-2 haematopoietic and lymphoid tissue GDSC1000, FIMM2
MDA-MB-453 breast GDSC1000, FIMM2
DU-4475 breast GDSC1000, FIMM2
MFM-223 breast GDSC1000, FIMM2
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Top molecular features associated with response to Epothilone B


Feature TypeStandardized
Nominal ANOVA
mRNA ANP32B GDSC1000 AAC 0.23 7e-10
mRNA SLC35F2 GDSC1000 AAC 0.22 9e-10
mRNA SLC25A37 GDSC1000 AAC 0.21 4e-09
mRNA NOB1 GDSC1000 AAC 0.21 4e-09
mRNA SETBP1 GDSC1000 AAC -0.2 5e-09
mRNA ATF1 GDSC1000 AAC 0.21 6e-09
mRNA NPM3 GDSC1000 AAC 0.2 7e-09
mRNA FAM110B GDSC1000 AAC -0.21 1e-08
mRNA C10orf2 GDSC1000 AAC 0.21 2e-08
mRNA GART GDSC1000 AAC 0.19 3e-08
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