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Elesclomol

Synonyms

SourcesNames Used
GDSC1000Elesclomol
PharmacoGx Elesclomol

External IDs

DatabaseIdentifier
Smiles: CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
Inchikey: BKJIXTWSNXCKJH-UHFFFAOYSA-N
Pubchem: 300471

Annotated Targets

HSPA1A

Cell lines tested with Elesclomol

895 cell lines have been tested with this compound, using data from 1 dataset(s).
OACM5-1 oesophagus GDSC10001
D-247MG central nervous system GDSC10001
MPP-89 pleura GDSC10001
VMRC-MELG skin GDSC10001
JEG-3 placenta GDSC10001
COLO-679 skin GDSC10001
H3255 lung GDSC10001
SNG-M endometrium GDSC10001
ALL-SIL haematopoietic and lymphoid tissue GDSC10001
U-698-M haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to Elesclomol


Feature TypeStandardized
Nominal ANOVA
mRNA CLDN3 GDSC1000 AAC -0.29 2e-11
mRNA KDF1 GDSC1000 AAC -0.27 6e-09
mRNA BSPRY GDSC1000 AAC -0.26 6e-11
mRNA CDH1 GDSC1000 AAC -0.25 4e-08
mRNA EPCAM GDSC1000 AAC -0.24 7e-07
mRNA MAL2 GDSC1000 AAC -0.24 8e-07
mRNA OVOL2 GDSC1000 AAC -0.24 5e-08
mRNA ESRP1 GDSC1000 AAC -0.23 1e-07
mRNA PRR15L GDSC1000 AAC -0.23 3e-08
mRNA ELF3 GDSC1000 AAC -0.23 1e-07
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