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SourcesNames Used
PharmacoGx dexamethasone

External IDs

Smiles: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
Pubchem: 5743

Annotated Targets

ANXA1, NOS2, NR0B1, NR3C1, NR3C2

Cell lines tested with dexamethasone

820 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to dexamethasone

Feature TypeStandardized
Nominal ANOVA
mRNA IGLL1 CTRPv2 AAC 0.4 6e-36
mRNA VPREB1 CTRPv2 AAC 0.36 7e-30
mRNA LCN6 CTRPv2 AAC 0.35 1e-29
mRNA RP11-216L13.16 CTRPv2 AAC 0.35 3e-28
mRNA ZCCHC7 CTRPv2 AAC 0.36 6e-27
mRNA EBF1 CTRPv2 AAC 0.35 2e-25
mRNA CLEC14A CTRPv2 AAC 0.33 1e-24
mRNA TTC7A CTRPv2 AAC 0.35 3e-23
mRNA GAB1 CTRPv2 AAC 0.33 3e-23
mRNA CD72 CTRPv2 AAC 0.33 3e-22
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