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decitabine

Synonyms

SourcesNames Used
CTRPv2decitabine
PharmacoGx decitabine

External IDs

DatabaseIdentifier
Smiles: Nc1ncn([C@@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1
Inchikey: XAUDJQYHKZQPEU-KVQBGUIXSA-N
Pubchem: 451668

Annotated Targets

DNMT3A, DNMT1

Cell lines tested with decitabine

849 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to decitabine


Feature TypeStandardized
Nominal ANOVA
mRNA DCK CTRPv2 AAC 0.29 8e-19
mRNA HNRNPA1L2 CTRPv2 AAC 0.29 1e-18
mRNA MBTD1 CTRPv2 AAC 0.28 2e-18
mRNA CDT1 CTRPv2 AAC 0.28 2e-18
mRNA DNMT1 CTRPv2 AAC 0.27 2e-18
mRNA CDCA7 CTRPv2 AAC 0.27 2e-18
mRNA USP49 CTRPv2 AAC 0.25 6e-17
mRNA SCAF4 CTRPv2 AAC 0.26 9e-17
mRNA ELF1 CTRPv2 AAC 0.3 2e-16
mRNA ZBED4 CTRPv2 AAC 0.26 2e-16
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