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SourcesNames Used
PharmacoGx Curcumin

External IDs

Smiles: COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
Pubchem: 969516

Annotated Targets

APP, CA1, CA12, CA14, CA2, CA4, CA6, CA9, CYP3A4, DNMT3B, EP300, MMP13, MMP9, NOS2, PTGS1, PTGS2, XDH

Cell lines tested with Curcumin

836 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to Curcumin

Feature TypeStandardized
Nominal ANOVA
mRNA ZBED4 CTRPv2 AAC 0.29 6e-13
mRNA BRD1 CTRPv2 AAC 0.19 3e-08
mRNA CBX2 CTRPv2 AAC 0.2 7e-08
mRNA FAM129B CTRPv2 AAC -0.22 7e-08
mRNA CLCF1 CTRPv2 AAC -0.19 4e-07
mRNA NAT10 CTRPv2 AAC 0.18 4e-07
mRNA SRGAP1 CTRPv2 AAC -0.19 4e-07
mRNA LMNB1 CTRPv2 AAC 0.19 5e-07
mRNA PTGR1 CTRPv2 AAC -0.18 5e-07
mRNA UGDH CTRPv2 AAC -0.18 7e-07
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