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clofarabine

Synonyms

SourcesNames Used
CTRPv2clofarabine
PharmacoGx clofarabine

External IDs

DatabaseIdentifier
Smiles: Nc1nc(Cl)nc2n(cnc12)C3OC(CO)C(O)C3F
Inchikey: WDDPHFBMKLOVOX-UHFFFAOYSA-N
Pubchem: 119182

Annotated Targets

POLA1, POLD1, POLE, RRM1, RRM2, RRM2B

Cell lines tested with clofarabine

854 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to clofarabine


Feature TypeStandardized
Nominal ANOVA
mRNA SLFN11 CTRPv2 AAC 0.36 3e-34
mRNA HMGB2 CTRPv2 AAC 0.32 8e-19
mRNA HNRNPA1L2 CTRPv2 AAC 0.27 3e-15
mRNA RAD54L CTRPv2 AAC 0.24 4e-15
mRNA HNRNPA1 CTRPv2 AAC 0.26 6e-15
mRNA KHDRBS1 CTRPv2 AAC 0.23 1e-14
mRNA HNRNPD CTRPv2 AAC 0.24 1e-14
mRNA SFPQ CTRPv2 AAC 0.23 1e-13
mRNA RFXAP CTRPv2 AAC 0.25 2e-13
mRNA HMGB1 CTRPv2 AAC 0.22 3e-13
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