1. Home/
  2. Compounds/
  3. ciclosporin

ciclosporin

Synonyms

SourcesNames Used
CTRPv2ciclosporin
PharmacoGx ciclosporin

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
Inchikey: PMATZTZNYRCHOR-KMSBSJHKSA-N
Pubchem: 6435893

Annotated Targets

PPID

Cell lines tested with ciclosporin

808 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
Download CSV

Tissues tested with ciclosporin

25 tissues have been tested with this compound, using data from 1 dataset(s).
pleuraCTRPv28
prostateCTRPv27
biliary tractCTRPv24
cervixCTRPv22
salivary glandCTRPv21
Download CSV
Download Data as CSV

Top molecular features associated with response to ciclosporin


Feature TypeStandardized
Nominal ANOVA
mRNA JCHAIN CTRPv2 AAC 0.24 4e-10
mRNA ENAM CTRPv2 AAC 0.23 3e-09
mRNA MZB1 CTRPv2 AAC 0.23 9e-08
mRNA FKBP11 CTRPv2 AAC 0.2 1e-07
mRNA PIGN CTRPv2 AAC 0.2 2e-07
mRNA INPP4A CTRPv2 AAC 0.2 2e-07
mRNA BTN1A1 CTRPv2 AAC 0.18 4e-07
mRNA LMAN1 CTRPv2 AAC 0.2 4e-07
mRNA RP4-583P15.14 CTRPv2 AAC 0.19 6e-07
mRNA CXXC1 CTRPv2 AAC 0.22 6e-07
Download CSV